Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24796341 | 0.86 | PER2 (0.36) | — | |
| SCHEMBL21389244 | 0.86 | MITF (0.36) | ALDH1A1L3MBTL1GAAMITFTSHR | |
| SCHEMBL24796422 | 0.86 | MITF (0.36) | ALDH1A1L3MBTL1GAAMITFTSHR | |
| SCHEMBL24796055 | 0.84 | CYP1A2 (0.35) | SMN1; SMN2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL24796340 | 0.84 | CYP1A2 (0.35) | SMN1; SMN2LMNAKMT2AALDH1A1L3MBTL1 | |
| SCHEMBL24796676 | 0.78 | HPGD (0.43) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389261 | 0.77 | ATM (0.50) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL21389270 | 0.77 | HPGD (0.44) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796295 | 0.76 | ATM (0.49) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL24796649 | 0.76 | ATM (0.46) | HPGDSMN1; SMN2LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |