SCHEMBL21389463

SCHEMBL21389463

NCCN1C(=O)[C@H]2C=C[C@@H]1C2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21389465 1.00 ALDH1A1 (0.31) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL24796036 1.00 ALDH1A1 (0.31) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL21389325 0.81 USP2 (0.38) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL21389415 0.81 SMN1; SMN2 (0.31) ALDH1A1MEN1RAB9AKMT2A
SCHEMBL5692758 0.77 USP2 (0.33) ALDH1A1
SCHEMBL24796420 0.73 KDM4E (0.32) ALDH1A1
SCHEMBL21389504 0.73 KDM4E (0.32) ALDH1A1
SCHEMBL21389322 0.73 KDM4E (0.32) ALDH1A1
SCHEMBL22518781 0.70 EHMT2 (0.50) ALDH1A1MEN1KMT2A
SCHEMBL22493942 0.70 EHMT2 (0.50) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. 2023-11-09 US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 US disclosed
US-11535660-B1 Modulators of G-protein coupled receptors Cannot Therapeutics, Inc. (US) 2022-12-27 US disclosed
WO-2019183577-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS CARMOT THERAPEUTICS, INC. (US) 2019-09-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357347-A1 MODULATORS OF G-PROTEIN COUPLED RECEPTORS GIPR, GLP1R, GCGR ALDH1A1 3305/4885MEN1 3167/4885RAB9A 664/4885
US-11535660-B1 Modulators of G-protein coupled receptors GIPR, GLP1R, GCGR ALDH1A1 3367/4885MEN1 3115/4885RAB9A 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.