Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 9/20 | 0.49 |
| ▸ | CDK2 | P24941 | 9/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 8/20 | 0.49 |
| ▸ | CDK4 | P11802 | 5/20 | 0.48 |
| ▸ | CDK1 | P06493 | 4/20 | 0.48 |
| ▸ | CCND1 | P24385 | 4/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.48 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.48 |
| ▸ | CCND2 | P30279 | 1/20 | 0.45 |
| ▸ | CCND3 | P30281 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179490 | 0.88 | CCNE1 (0.52) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL21369612 | 0.81 | CCNE1 (0.45) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL2174552 | 0.81 | CA1 (0.49) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL19727246 | 0.80 | CDK2 (0.47) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL13158536 | 0.77 | CCNE1 (0.48) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL20049878 | 0.75 | CCNE1 (0.43) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL13543136 | 0.75 | SMN1; SMN2 (0.60) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL2175131 | 0.74 | RAB9A (0.60) | CCNE1CDK2CDK4CDK1LMNA | |
| SCHEMBL21770026 | 0.73 | CDK2 (0.53) | CCNE1CDK2CCNE2CDK4CDK1 | |
| SCHEMBL1763394 | 0.73 | CCNE1 (0.48) | CCNE1CDK2CCNE2CDK4CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290636-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | INTELLIKINE LLC | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290636-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS | PIK3CA, PIK3CG, PIK3CB | CCNE1 1941/4885CDK2 128/4885CCNE2 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.