Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 7/20 | 0.41 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 2/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20877512 | 0.89 | CA1 (0.47) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL20064076 | 0.88 | PSEN1 (0.47) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL15921777 | 0.83 | CA1 (0.50) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL12241503 | 0.81 | RAB9A (0.52) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL21389733 | 0.81 | CCNE1 (0.49) | CCNE2CCNE1CDK2CCNB2CDK1 | |
| SCHEMBL13039 | 0.80 | FPR3 (0.54) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL27819346 | 0.80 | CA1 (0.47) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL13266901 | 0.80 | CA1 (0.47) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL640631 | 0.80 | FFAR2 (0.52) | CA1CA2CCNE2CCNE1CDK2 | |
| SCHEMBL29170444 | 0.79 | CA1 (0.47) | CA1CA2CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973164-B2 | Quinoline derivatives | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | disclosed |