Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 10/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390247 | 0.85 | ATF4 (0.59) | ATF4 | |
| SCHEMBL23332818 | 0.74 | ATF4 (0.42) | ATF4SCN9AHTR7 | |
| SCHEMBL25963726 | 0.74 | ATF4 (0.42) | ATF4SCN9AHTR7 | |
| SCHEMBL21390203 | 0.73 | ATF4 (0.49) | ATF4SCN9AF10 | |
| SCHEMBL25963238 | 0.72 | ATF4 (0.53) | ATF4SCN9A | |
| SCHEMBL21390249 | 0.72 | ATF4 (0.63) | ATF4 | |
| SCHEMBL23294739 | 0.72 | ATF4 (0.63) | ATF4 | |
| SCHEMBL21390210 | 0.69 | ATF4 (0.45) | ATF4SCN9A | |
| SCHEMBL28896405 | 0.69 | CNR1 (0.60) | ATF4SCN9AHTR7 | |
| SCHEMBL23333309 | 0.69 | SCN9A (0.33) | ATF4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |