Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 9/20 | 0.49 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390249 | 0.83 | ATF4 (0.63) | ATF4KCNH2 | |
| SCHEMBL23294739 | 0.83 | ATF4 (0.63) | ATF4KCNH2 | |
| SCHEMBL21390251 | 0.81 | ATF4 (0.51) | ATF4F10SCN9ASCN7AKCNH2 | |
| SCHEMBL23332820 | 0.81 | ATF4 (0.47) | ATF4SCN9A | |
| SCHEMBL21390328 | 0.81 | ATF4 (0.51) | ATF4F10SCN9ASCN7AKCNH2 | |
| SCHEMBL24997981 | 0.77 | ATF4 (0.40) | ATF4SCN9A | |
| SCHEMBL30053049 | 0.77 | ATF4 (0.40) | ATF4SCN9A | |
| SCHEMBL24997259 | 0.75 | ATF4 (0.43) | ATF4KCNH2 | |
| SCHEMBL23294632 | 0.73 | ATF4 (0.54) | ATF4KCNH2 | |
| SCHEMBL21390156 | 0.73 | ATF4 (0.54) | ATF4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183589-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. (US) | 2019-09-26 | — | — | WO | disclosed |