Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 8/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23332965 | 0.88 | ATF4 (0.39) | ATF4SCN9A | |
| SCHEMBL25963726 | 0.86 | ATF4 (0.42) | ATF4SCN9AMAPTL3MBTL1 | |
| SCHEMBL23332865 | 0.85 | ATF4 (0.37) | ATF4SCN9A | |
| SCHEMBL23332907 | 0.83 | ATF4 (0.39) | ATF4SCN9A | |
| SCHEMBL23332842 | 0.83 | ATF4 (0.37) | ATF4L3MBTL1 | |
| SCHEMBL23333260 | 0.82 | SCN9A (0.49) | SCN9A | |
| SCHEMBL23332914 | 0.81 | SCN9A (0.44) | SCN9A | |
| SCHEMBL23332841 | 0.81 | SCN9A (0.46) | SCN9A | |
| SCHEMBL21390203 | 0.81 | ATF4 (0.49) | ATF4SCN9A | |
| SCHEMBL23332818 | 0.81 | ATF4 (0.42) | ATF4SCN9AMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130308-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | DENALI THERAPEUTICS INC. | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130308-A1 | MODULATORS OF EUKARYOTIC INITIATION FACTOR 2 | EIF2A, EIF4A2, EIF4EBP1 | ATF4 118/4885SCN9A 3136/4885MAPT 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.