Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GBA1 | P04062 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390491 | 0.94 | CYP19A1 (0.43) | CYP19A1CYP3A4CYP2C9ALDH1A1GBA1 | |
| SCHEMBL21390292 | 0.88 | CYP19A1 (0.44) | CYP19A1CYP3A4ALDH1A1GBA1KDM4E | |
| SCHEMBL21390620 | 0.88 | MAPT (0.41) | CYP3A4CYP2C9ALDH1A1KDM4EMEN1 | |
| SCHEMBL21390745 | 0.88 | GBA1 (0.44) | CYP3A4CYP2C9ALDH1A1GBA1KDM4E | |
| SCHEMBL21390623 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4ETSHRMAPK1HSD17B10 | |
| SCHEMBL21390602 | 0.79 | PTGS2 (0.50) | CYP19A1ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL21390636 | 0.79 | CYP2A6 (0.46) | CYP19A1CYP3A4ALDH1A1GBA1KDM4E | |
| SCHEMBL21390740 | 0.78 | CYP19A1 (0.44) | CYP19A1CYP3A4ALDH1A1GBA1KDM4E | |
| SCHEMBL21390728 | 0.78 | MEN1 (0.47) | CYP3A4ALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL21390741 | 0.76 | CYP2A6 (0.48) | CYP19A1ALDH1A1KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292309-A1 | HIGH POLYMER, MIXTURE CONTAINING SAME, COMPOSITION, ORGANIC ELECTRONIC COMPONENT, AND MONOMER FOR POLYMERIZATION | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-09-26 | — | — | US | disclosed |