Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23776020 | 0.96 | NR3C2 (0.46) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL13432686 | 0.94 | NR3C2 (0.43) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL20160922 | 0.92 | NR3C2 (0.53) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL18377018 | 0.92 | NR3C2 (0.53) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL3368539 | 0.90 | NR3C2 (0.55) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL9565100 | 0.90 | NR3C2 (0.50) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL6932587 | 0.88 | NR3C2 (0.52) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL29303446 | 0.86 | HSD17B1 (0.42) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL20681739 | 0.86 | NR3C2 (0.51) | NR3C2MAPTALDH1A1HPGDCRHBP | |
| SCHEMBL13370980 | 0.84 | ESR1 (0.47) | NR3C2MAPTCRHBPCRHR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020225071-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-11-12 | — | — | WO | disclosed |
| WO-2019179909-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | WO | disclosed |