SCHEMBL20160922

SCHEMBL20160922

CCN(c1ccccc1)c1ccc(-c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 1/20 0.53
MAPT P10636 4/20 0.46
ALDH1A1 P00352 4/20 0.46
HPGD P15428 3/20 0.46
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TAAR1 Q96RJ0 1/20 0.43
KDM4E B2RXH2 1/20 0.43
AGTR1 P30556 1/20 0.43
TSHR P16473 2/20 0.42
GLA P06280 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CNR2 P34972 1/20 0.41
KDM4C Q9H3R0 1/20 0.40
APAF1 O14727 1/20 0.40
CASP3 P42574 1/20 0.40
CASP6 P55212 1/20 0.40
SENP8 Q96LD8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18377018 1.00 NR3C2 (0.53) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL3368539 0.98 NR3C2 (0.55) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL9565100 0.98 NR3C2 (0.50) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL6932587 0.95 NR3C2 (0.52) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL20681739 0.93 NR3C2 (0.51) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL21390743 0.92 NR3C2 (0.47) NR3C2MAPTALDH1A1HPGDCRHBP
SCHEMBL7149333 0.91 NR3C2 (0.60) NR3C2MAPTALDH1A1CRHBPCRHR2
SCHEMBL13241976 0.90 CYP2C19 (0.46) NR3C2MAPTALDH1A1HPGDTAAR1
SCHEMBL6567347 0.88 NR3C2 (0.57) NR3C2MAPTALDH1A1CRHBPCRHR2
SCHEMBL409370 0.88 NR3C2 (0.57) NR3C2MAPTALDH1A1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-03-03 US disclosed
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180138421-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY2, NR2E3, CRY1 NR3C2 1030/4885MAPT 530/4885ALDH1A1 928/4885
US-10580996-B2 Polycyclic compound and organic light-emitting element comprising same CRY2, NR2E3, CRY1 NR3C2 1030/4885MAPT 530/4885ALDH1A1 928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.