Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391182 | 0.97 | PDE2A (0.31) | PDE2APDE10AALOX5AP | |
| SCHEMBL21391068 | 0.94 | PDE2A (0.30) | PDE2APDE10A | |
| SCHEMBL21390884 | 0.84 | BRD4 (0.33) | ALOX5AP | |
| SCHEMBL21391053 | 0.84 | ALOX5AP (0.32) | ALOX5AP | |
| SCHEMBL21390794 | 0.83 | — | — | |
| SCHEMBL21390922 | 0.80 | ALOX5AP (0.31) | ALOX5AP | |
| SCHEMBL21390672 | 0.79 | BRD4 (0.34) | PDE2APDE10A | |
| SCHEMBL30315545 | 0.79 | KCNQ2 (0.32) | PDE2APDE10A | |
| SCHEMBL21354720 | 0.79 | KCNQ2 (0.32) | PDE2APDE10A | |
| SCHEMBL21390820 | 0.77 | ACSS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |