Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 12/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390879 | 0.79 | MCHR1 (0.35) | PTGDR2MCHR1HTR7 | |
| SCHEMBL21391014 | 0.79 | MCHR1 (0.35) | PTGDR2MCHR1HTR7 | |
| SCHEMBL17582729 | 0.78 | MCHR1 (0.38) | MCHR1SCN9A | |
| SCHEMBL21390876 | 0.72 | MCHR1 (0.36) | PTGDR2MCHR1 | |
| SCHEMBL21390851 | 0.70 | RORC (0.31) | — | |
| SCHEMBL21391008 | 0.68 | PDE2A (0.31) | — | |
| SCHEMBL21390957 | 0.67 | NTRK1 (0.33) | HTR7 | |
| SCHEMBL21390841 | 0.67 | HDAC1 (0.35) | — | |
| SCHEMBL21391109 | 0.66 | — | — | |
| SCHEMBL21390840 | 0.66 | HDAC1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |