Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.31 |
| ▸ | BMI1 | P35226 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390879 | 1.00 | MCHR1 (0.35) | MCHR1PTGDR2S1PR1LMNAL3MBTL1 | |
| SCHEMBL18791680 | 0.80 | CSNK1D (0.40) | MCHR1S1PR1CSNK1DCCRL2BMI1 | |
| SCHEMBL20111052 | 0.80 | CSNK1D (0.40) | MCHR1S1PR1CSNK1DCCRL2BMI1 | |
| SCHEMBL18791682 | 0.80 | CSNK1D (0.40) | MCHR1S1PR1CSNK1DCCRL2BMI1 | |
| SCHEMBL21390878 | 0.79 | PTGDR2 (0.34) | MCHR1PTGDR2HTR7 | |
| SCHEMBL21390876 | 0.79 | MCHR1 (0.36) | MCHR1PTGDR2 | |
| SCHEMBL21771777 | 0.73 | ALK (0.37) | MCHR1CSNK1D | |
| SCHEMBL21390906 | 0.71 | PDE2A (0.31) | — | |
| SCHEMBL21391033 | 0.71 | ACSS2 (0.33) | S1PR1 | |
| SCHEMBL21390907 | 0.71 | RORC (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |