Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390948 | 0.88 | CYP11B2 (0.59) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL1014609 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL1014610 | 0.87 | SMN1; SMN2 (0.58) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| Hydrochloric Acid SCHEMBL31587373 | 0.86 | CCR3 (0.62) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL18731435 | 0.84 | KDM4E (0.65) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL13543527 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL3523976 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL21025758 | 0.82 | KDM4E (0.62) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL1391258 | 0.78 | KDM4E (0.97) | ALDH1A1KDM4EMAPTGFERTDP1 | |
| SCHEMBL15345129 | 0.78 | MCHR1 (0.62) | ALDH1A1KDM4EMAPTGFERTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |