Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 15/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 12/20 | 0.59 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.56 |
| ▸ | CDK9 | P50750 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390931 | 0.88 | ALDH1A1 (0.62) | CYP11B2CYP11B1CCNT1CDK9KDM4E | |
| SCHEMBL17586642 | 0.82 | CDK9 (0.56) | CYP11B2CYP11B1CCNT1CDK9KDM4E | |
| SCHEMBL17586640 | 0.81 | CYP11B2 (0.58) | CYP11B2CYP11B1CCNT1CDK9ADRB1 | |
| SCHEMBL21026145 | 0.79 | CDK9 (0.54) | CYP11B2CYP11B1CCNT1CDK9KDM4E | |
| SCHEMBL27359733 | 0.79 | CDK9 (0.54) | CYP11B2CYP11B1CCNT1CDK9KDM4E | |
| SCHEMBL11901850 | 0.79 | PIK3CD (0.51) | CYP11B2CYP11B1CCNT1CDK9ADRB1 | |
| SCHEMBL2493364 | 0.79 | CDK9 (0.60) | CYP11B2CYP11B1CCNT1CDK9KDM4E | |
| SCHEMBL6843573 | 0.78 | IDO1 (0.47) | CYP11B2CYP11B1ADRB1ADRA2ACYP19A1 | |
| SCHEMBL7717397 | 0.78 | IDO1 (0.47) | CYP11B2CYP11B1ADRB1ADRA2ACYP19A1 | |
| SCHEMBL7161656 | 0.78 | IDO1 (0.47) | CYP11B2CYP11B1ADRB1ADRA2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |