⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391082 | 0.86 | — | — | |
| SCHEMBL21390885 | 0.85 | AR (0.32) | — | |
| SCHEMBL21391062 | 0.84 | ACSS2 (0.33) | — | |
| SCHEMBL23132029 | 0.83 | HDAC1 (0.33) | — | |
| SCHEMBL21390794 | 0.81 | — | — | |
| SCHEMBL21390935 | 0.80 | HDAC1 (0.33) | — | |
| SCHEMBL21390889 | 0.77 | — | — | |
| SCHEMBL21354647 | 0.76 | KCNQ3 (0.35) | — | |
| SCHEMBL21391177 | 0.74 | RORC (0.32) | — | |
| SCHEMBL21391032 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055538-A1 | METHODS OF USE FOR KV7 CHANNEL ACTIVATORS | KNOPP BIOSCIENCES LLC (US) | 2021-03-25 | — | — | WO | disclosed |
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |