Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390934 | 0.92 | CYP11B2 (0.32) | CYP11B2CYP11B1BRD4CREBBP | |
| SCHEMBL21390713 | 0.80 | CYP11B2 (0.36) | CYP11B2CYP11B1 | |
| SCHEMBL21390950 | 0.80 | CYP11B2 (0.36) | CYP11B2CYP11B1 | |
| SCHEMBL21390721 | 0.78 | CYP11B2 (0.35) | CYP11B2CYP11B1 | |
| SCHEMBL16084143 | 0.78 | P2RX7 (0.41) | CYP11B2CYP11B1CNR1CNR2 | |
| SCHEMBL21390976 | 0.77 | CYP11B2 (0.37) | CYP11B2CYP11B1 | |
| SCHEMBL21390982 | 0.76 | TDP1 (0.35) | CYP11B2CYP11B1 | |
| SCHEMBL21390858 | 0.76 | CYP11B2 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL24847872 | 0.75 | PIK3CA (0.36) | CYP11B2BRD4CREBBPCNR1 | |
| SCHEMBL16084287 | 0.75 | GBA1 (0.37) | CYP11B2CYP11B1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |