Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390964 | 0.83 | PDE2A (0.35) | PDE2AAGTR1AGTR2 | |
| SCHEMBL21390834 | 0.79 | PDE4B (0.35) | PDE2A | |
| SCHEMBL21390833 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL21390832 | 0.72 | PDE2A (0.33) | PDE2A | |
| SCHEMBL21390780 | 0.71 | IRAK4 (0.31) | PDE2A | |
| SCHEMBL21390829 | 0.69 | CNR2 (0.38) | — | |
| SCHEMBL19277995 | 0.69 | PDE2A (0.36) | PDE2A | |
| SCHEMBL21391146 | 0.69 | — | — | |
| SCHEMBL21390963 | 0.68 | PDE2A (0.31) | PDE2A | |
| SCHEMBL21390968 | 0.66 | PDE2A (0.33) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |