Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 19/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390780 | 0.82 | IRAK4 (0.31) | — | |
| SCHEMBL21390832 | 0.81 | PDE2A (0.33) | — | |
| SCHEMBL21390917 | 0.79 | PDE2A (0.30) | — | |
| SCHEMBL21391146 | 0.79 | — | — | |
| SCHEMBL21390906 | 0.77 | PDE2A (0.31) | — | |
| SCHEMBL19278426 | 0.77 | ROCK2 (0.39) | CNR2CYP3A4SCN9A | |
| SCHEMBL21390904 | 0.76 | PDE2A (0.32) | — | |
| SCHEMBL21390964 | 0.75 | PDE2A (0.35) | — | |
| SCHEMBL21390903 | 0.75 | RORC (0.32) | — | |
| SCHEMBL21391128 | 0.75 | MEN1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |