SCHEMBL21391009

SCHEMBL21391009

CC(O)(CC(=O)CCCCc1nc2ccc(Cl)nc2n1C1CCC1)CC(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 3/20 0.34
CYP11B1 P15538 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21390950 0.87 CYP11B2 (0.36) CYP11B2CYP11B1
SCHEMBL21391006 0.85 CYP11B2 (0.36) CYP11B2CYP11B1
SCHEMBL21390973 0.84 CYP11B2 (0.34) CYP11B2CYP11B1
SCHEMBL21391005 0.82
SCHEMBL21391133 0.81 CYP11B1 (0.33) CYP11B2CYP11B1
SCHEMBL21390976 0.79 CYP11B2 (0.37) CYP11B2CYP11B1
SCHEMBL21390711 0.78 CYP11B2 (0.32) CYP11B2CYP11B1
SCHEMBL19277824 0.78 CYP11B2 (0.36) CYP11B2CYP11B1
SCHEMBL21391073 0.78 PDE10A (0.37) CYP11B2
SCHEMBL21390721 0.78 CYP11B2 (0.35) CYP11B2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019183148-A1 KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE KNOPP BIOSCIENCES LLC (US) 2019-09-26 WO disclosed