Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391124 | 0.86 | HTR3E (0.35) | CYP11B2SMN1; SMN2GRM2ALDH1A1 | |
| SCHEMBL21391120 | 0.84 | TBXA2R (0.35) | PTGDR2TBXA2RSMN1; SMN2GRM2ALDH1A1 | |
| SCHEMBL21391002 | 0.83 | CYP11B1 (0.34) | CYP11B2CYP11B1AGTR1AGTR2SMN1; SMN2 | |
| SCHEMBL21391006 | 0.81 | CYP11B2 (0.36) | CYP11B2CYP11B1 | |
| SCHEMBL21390858 | 0.80 | CYP11B2 (0.33) | CYP11B2CYP11B1 | |
| SCHEMBL21390973 | 0.79 | CYP11B2 (0.34) | CYP11B2CYP11B1SMN1; SMN2ALDH1A1 | |
| SCHEMBL21390934 | 0.79 | CYP11B2 (0.32) | CYP11B2CYP11B1 | |
| SCHEMBL21390716 | 0.79 | CPT1A (0.37) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL21390713 | 0.79 | CYP11B2 (0.36) | CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL21390950 | 0.79 | CYP11B2 (0.36) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |