Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.57 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389597 | 0.92 | NR1H4 (0.60) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL21391360 | 0.87 | PPARA (0.55) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL21389589 | 0.85 | MEN1 (0.67) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10473599 | 0.85 | PPARA (0.67) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL21391370 | 0.83 | PPARA (0.60) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10473704 | 0.83 | PPARA (0.65) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10641341 | 0.82 | PPARA (0.55) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10641344 | 0.82 | PPARA (0.55) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10641355 | 0.80 | PPARA (0.52) | NR1H4PPARATSHRCYP2C8CYP2C9 | |
| SCHEMBL10641349 | 0.80 | PPARA (0.52) | NR1H4PPARATSHRCYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2020-05-12 | — | — | US | disclosed |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10647673-B2 | Acetophenone compound, preparation method thereof, and application thereof in fatty liver prevention and treatment | LIPC, CYP27A1, HSD17B10 | NR1H4 168/4885PPARA 14/4885TSHR 3696/4885 |
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | LIPC, CYP27A1, HSD17B10 | NR1H4 168/4885PPARA 14/4885TSHR 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.