Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MDH1 | P40925 | 2/20 | 0.57 |
| ▸ | MDH2 | P40926 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21389593 | 0.85 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL22221480 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28577219 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL29768387 | 0.82 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL2610067 | 0.82 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21391273 | 0.81 | SMN1; SMN2 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL22221475 | 0.81 | PPARA (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL22221585 | 0.80 | CNR2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL21391285 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL22221597 | 0.78 | PPARA (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | Nanjing Bioenergy Medicine Science & Technology Co., Ltd. (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292153-A1 | Acetophenone Compound, Preparation Method Thereof, And Application Thereof In Fatty Liver Prevention And Treatment | LIPC, CYP27A1, HSD17B10 | CYP1A2 167/4885CYP3A4 283/4885CYP2C9 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.