Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.58 |
| ▸ | KIT | P10721 | 1/20 | 0.58 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.58 |
| ▸ | BRAF | P15056 | 12/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20695991 | 0.89 | CSF1R (0.70) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL21391318 | 0.87 | CSF1R (0.55) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL20695981 | 0.81 | KIT (0.86) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL20707299 | 0.81 | CSF1R (0.72) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL21391367 | 0.79 | KIT (0.68) | CSF1RPDGFRBKITDDR1NAMPT | |
| SCHEMBL21391377 | 0.78 | KIT (0.66) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL21391410 | 0.77 | KIT (0.60) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL21391415 | 0.77 | CSF1R (0.60) | CSF1RPDGFRBKITDDR1BRAF | |
| SCHEMBL21385153 | 0.77 | KIT (0.66) | CSF1RPDGFRBKITDDR1NAMPT | |
| SCHEMBL29634986 | 0.77 | KIT (0.66) | CSF1RPDGFRBKITDDR1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |