Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.45 |
| ▸ | RBP4 | P02753 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391375 | 1.00 | KIT (0.46) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391413 | 0.92 | KIT (0.45) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391396 | 0.92 | KIT (0.45) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391328 | 0.87 | KIT (0.57) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391400 | 0.84 | KIT (0.63) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391374 | 0.84 | KIT (0.63) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391402 | 0.81 | KIT (0.55) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391407 | 0.81 | KIT (0.55) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL20695973 | 0.79 | KIT (0.75) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391381 | 0.77 | KIT (0.61) | KITABL1CSF1RPDGFRBDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |