Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 4/20 | 0.45 |
| ▸ | ABL1 | P00519 | 3/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391396 | 1.00 | KIT (0.45) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391401 | 0.92 | KIT (0.46) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391375 | 0.92 | KIT (0.46) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391328 | 0.86 | KIT (0.57) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391419 | 0.82 | CSF1R (0.44) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391408 | 0.82 | CSF1R (0.44) | KITCSF1RPDGFRBDDR1ALDH1A1 | |
| SCHEMBL21391398 | 0.81 | KIT (0.54) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391411 | 0.81 | KIT (0.54) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391417 | 0.81 | ALDH1A1 (0.53) | KITABL1CSF1RPDGFRBDDR1 | |
| SCHEMBL21391399 | 0.81 | ALDH1A1 (0.53) | KITABL1CSF1RPDGFRBDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |