Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 6/20 | 0.54 |
| ▸ | CSF1R | P07333 | 2/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.54 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | BLK | P51451 | 1/20 | 0.44 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391403 | 0.88 | KIT (0.69) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391376 | 0.85 | KIT (0.63) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391410 | 0.85 | KIT (0.60) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391406 | 0.84 | KIT (0.57) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391417 | 0.79 | ALDH1A1 (0.53) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391399 | 0.79 | ALDH1A1 (0.53) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391340 | 0.74 | KIT (0.59) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL21391337 | 0.72 | KCNK3 (0.56) | ALDH1A1NPSR1MAPTMEN1MAPK1 | |
| SCHEMBL21391331 | 0.72 | KIT (0.77) | KITCSF1RPDGFRBDDR1ABL1 | |
| SCHEMBL20707298 | 0.71 | KIT (0.89) | KITCSF1RPDGFRBDDR1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |