Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.46 |
| ▸ | KIT | P10721 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391417 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1PABPC1EIF4HKIT | |
| SCHEMBL21391419 | 0.84 | CSF1R (0.44) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391408 | 0.84 | CSF1R (0.44) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391398 | 0.82 | KIT (0.54) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391411 | 0.82 | KIT (0.54) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391413 | 0.81 | KIT (0.45) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391396 | 0.81 | KIT (0.45) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391404 | 0.79 | KIT (0.54) | ALDH1A1NPSR1PABPC1EIF4HKIT | |
| SCHEMBL21391374 | 0.77 | KIT (0.63) | ALDH1A1KITCSF1RPDGFRBDDR1 | |
| SCHEMBL21391400 | 0.77 | KIT (0.63) | ALDH1A1KITCSF1RPDGFRBDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178801-A1 | NOVEL PHENOXY PIPERIDINE DERIVATIVE AND USES THEREOF | 中国科学院合肥物质科学研究院 | 2019-09-26 | — | — | WO | disclosed |