SCHEMBL21391531

SCHEMBL21391531

COC(c1cccc(O[Si](C)(C)C(C)(C)C)c1)P(=O)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.37
CA1 P00915 4/20 0.37
CA9 Q16790 4/20 0.37
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
PREP P48147 2/20 0.33
ALOX15 P16050 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8454707 0.80 AOC3 (0.44) CA1CA9ALDH1A1POLB
SCHEMBL21391528 0.79 CA12 (0.40) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL30514294 0.79 CA12 (0.40) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL15242469 0.75 CA1 (0.42) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL19745616 0.74 CA12 (0.41) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL29306881 0.74 CA12 (0.40) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL343105 0.73 CA12 (0.40) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL21391571 0.73 ALOX15 (0.33) ALOX15
SCHEMBL7706827 0.73 CA1 (0.50) CA12CA1CA9HSP90AA1HSP90AB1
SCHEMBL26304030 0.72 ACP3 (0.46) ALOX15ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12281092-B2 Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte SYSMEX CORPORATION (JP) 2025-04-22 US disclosed
WO-2024147125-A1 CYCLOBUTYL-SUBSTITUTED PHENOXY-DIOXETANES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-07-11 WO disclosed
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-03 US disclosed
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-03 US disclosed
EP-4219651-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE SYSMEX CORPORATION (JP) 2023-08-02 EP disclosed
US-20220047725-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-02-17 US disclosed
US-11179482-B2 Chemiluminescent probes for diagnostics and in vivo imaging RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2021-11-23 US disclosed
EP-3408349-B1 CHEMILUMINESCENT FLUOROPHOR-LINKED ADAMANTYLENE-DIOXETANE PROBES AS DIAGNOSTICS OR IN-VIVO IMAGING SENSORS UNIV RAMOT (IL) 2021-03-31 EP disclosed
US-20200237932-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2020-07-30 US disclosed
US-10660974-B2 Chemiluminescent probes for diagnostics and in vivo imaging RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2020-05-26 US disclosed
US-20190290787-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10660974-B2 Chemiluminescent probes for diagnostics and in vivo imaging DAXX, DCAF15, DCAF1 CA12 293/4885CA1 1716/4885CA9 568/4885
US-20200237932-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, CDY1; CDY1B CA12 59/4885CA1 504/4885CA9 370/4885
US-12281092-B2 Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte JAK2, MPO, PEAK1 CA12 67/4885CA1 267/4885CA9 11/4885
US-20220047725-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, CDY1; CDY1B CA12 59/4885CA1 504/4885CA9 370/4885
US-11179482-B2 Chemiluminescent probes for diagnostics and in vivo imaging DAXX, DCAF15, CDY1; CDY1B CA12 59/4885CA1 504/4885CA9 370/4885
US-20190290787-A1 CHEMILUMINESCENT PROBES FOR DIAGNOSTICS AND IN VIVO IMAGING DAXX, DCAF15, DCAF1 CA12 293/4885CA1 1716/4885CA9 568/4885
US-20230242499-A1 COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE JAK2, MPO, PEAK1 CA12 67/4885CA1 267/4885CA9 11/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.