Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 15/20 | 0.56 |
| ▸ | MAOB | P27338 | 14/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29859512 | 0.78 | DHODH (1.00) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL28343270 | 0.78 | DHODH (1.00) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL19631461 | 0.78 | DHODH (1.00) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL25613763 | 0.75 | DHODH (0.85) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL21391587 | 0.74 | DHODH (0.50) | DHODHMEN1KMT2AMAPTGAA | |
| SCHEMBL25613721 | 0.73 | DHODH (0.72) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL25614403 | 0.72 | DHODH (0.70) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL4101065 | 0.69 | MEN1 (1.00) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL4101069 | 0.69 | MEN1 (1.00) | DHODHMAOAMAOBMEN1KMT2A | |
| SCHEMBL10810440 | 0.68 | ALOX5 (0.76) | DHODHMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290620-A1 | APPLICATIONS OF NOVEL THIAZOLE DERIVATIVE IN TREATING INFLAMMATORY BOWEL DISEASES | FABP2, SLC10A2, ALPI | DHODH 803/4885MAOA 4074/4885MAOB 3732/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.