SCHEMBL21391588

SCHEMBL21391588

Cc1ccc(C)c(OC2CCC3(C)C4CCC5(C)C(C(C)CCCC(C)C)CCC5C4CCC3C2(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
SRD5A1 P18405 6/20 0.46
SRD5A2 P31213 3/20 0.46
INPP5D Q92835 1/20 0.46
FNTA P49354 3/20 0.44
FNTB P49356 3/20 0.44
NPC1L1 Q9UHC9 1/20 0.44
IGF1R P08069 1/20 0.44
MET P08581 1/20 0.44
SRC P12931 1/20 0.44
AXL P30530 1/20 0.44
KDR P35968 1/20 0.44
MAP2K1 Q02750 1/20 0.44
PTK2 Q05397 1/20 0.44
AURKB Q96GD4 1/20 0.44
ALK Q9UM73 1/20 0.44
CDC25A P30304 3/20 0.43
POLA1 P09884 1/20 0.43
USP2 O75604 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391589 0.87 GPBAR1 (0.38) USP2LMNARORC
SCHEMBL21401408 0.87 RORC (0.47) USP2LMNARORC
SCHEMBL257593 0.84 CYP2D6 (0.48) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL9999572 0.84 CYP2D6 (0.48) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL15806705 0.81 CYP2D6 (0.48) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL257580 0.77 CYP2D6 (0.40) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL15328611 0.77 CYP2D6 (0.49) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL27656263 0.77 CYP2D6 (0.49) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL16243996 0.76 CYP2D6 (0.47) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D
SCHEMBL15329098 0.76 CYP2D6 (0.47) CYP2D6CYP2C19SRD5A1SRD5A2INPP5D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182071-A1 LIQUID CRYSTAL ALIGNMENT AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed