SCHEMBL21391589

SCHEMBL21391589

C/C=C\CCC(C)C1CCC2C3CCC4C(C)(C)C(Oc5cc(C)ccc5C)CCC4(C)C3CCC12C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 5/20 0.38
EPHA2 P29317 5/20 0.38
HSD17B10 Q99714 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
AKR1B10 O60218 2/20 0.38
AKR1B1 P15121 2/20 0.38
LMNA P02545 2/20 0.38
EFNA1 P20827 1/20 0.38
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38
PSENEN Q9NZ42 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
RORC P51449 1/20 0.35
HIF1A Q16665 2/20 0.35
VDR P11473 2/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21401408 0.89 RORC (0.47) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL21391588 0.87 CYP2D6 (0.46) LMNARORCUSP2
SCHEMBL257586 0.85 GPBAR1 (0.38) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL16982189 0.81 GPBAR1 (0.46) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL19725098 0.76 GPBAR1 (0.47) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL10015980 0.75 RORC (0.47) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL9999583 0.74 RORC (0.46) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL15495613 0.74 RORC (0.47) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL15083732 0.73 GPBAR1 (0.44) GPBAR1EPHA2HSD17B10TDP1AKR1B10
SCHEMBL257593 0.72 CYP2D6 (0.48) LMNARORCUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182071-A1 LIQUID CRYSTAL ALIGNMENT AGENT, POLYMER FOR OBTAINING SAME, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME 日産化学株式会社 2019-09-26 WO disclosed