Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21781196 | 0.87 | TSPO (0.51) | TSPOMAPTHTTMEN1KMT2A | |
| SCHEMBL21391622 | 0.85 | MAPT (0.44) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL17854085 | 0.84 | GPR3 (0.57) | TSPOMAPTLMNAHTTMEN1 | |
| SCHEMBL17229602 | 0.84 | GPR3 (0.57) | TSPOMAPTLMNAHTTMEN1 | |
| SCHEMBL24315418 | 0.83 | TSPO (0.42) | TSPOMAPTLMNAHTTMEN1 | |
| SCHEMBL18574393 | 0.83 | MAPT (0.44) | TSPOMAPTLMNAHTTMEN1 | |
| SCHEMBL21787843 | 0.83 | TSPO (0.42) | TSPOMAPTLMNAHTTMEN1 | |
| SCHEMBL19785205 | 0.81 | KDM4E (0.50) | TSPOMAPTLMNAHTTKDM4E | |
| SCHEMBL11917680 | 0.81 | KDM4E (0.50) | TSPOMAPTLMNAHTTKDM4E | |
| SCHEMBL17178970 | 0.81 | KDM4E (0.50) | TSPOMAPTLMNAHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119590-A1 | POLYMERS WITH AMINE-GROUP-CONTAINING REPEATING UNITS | MERCK PATENT GMBH (DE) | 2022-04-21 | — | — | US | disclosed |
| US-20210277176-A1 | FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER | MERCK PATENT GMBH (DE) | 2021-09-09 | — | — | US | disclosed |
| US-20190296242-A1 | POLYMERS WITH ASYMMETRIC REPEATING UNITS | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |