Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391872 | 0.94 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL19806810 | 0.90 | HTT (0.51) | CYP1A2CYP2C9CYP2C19MEN1LMNA | |
| 1-Isopentoxy-2-Butoxybenzene SCHEMBL2848360 | 0.87 | CYP1A2 (0.56) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL6651604 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL30096940 | 0.86 | CYP1A2 (0.63) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL9387360 | 0.84 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL2859001 | 0.84 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL2245919 | 0.84 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL1778134 | 0.84 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 | |
| SCHEMBL1964196 | 0.84 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19MEN1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11034720-B2 | Thiol-yne based peptide stapling and uses thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-06-15 | — | — | US | disclosed |
| US-20190292218-A1 | THIOL-YNE BASED PEPTIDE STAPLING AND USES THEREOF | UNIVERSITY OF UTAH | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292218-A1 | THIOL-YNE BASED PEPTIDE STAPLING AND USES THEREOF | IAPP, TP53, GLP1R | CYP1A2 4369/4885CYP2C9 4111/4885CYP2C19 4281/4885 |
| US-11034720-B2 | Thiol-yne based peptide stapling and uses thereof | IAPP, TP53, GLP1R | CYP1A2 4369/4885CYP2C9 4111/4885CYP2C19 4281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.