Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391872 | 0.92 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9HTTTDP1 | |
| SCHEMBL27555724 | 0.90 | HTT (0.56) | CYP1A2CYP2C19CYP2C9HTTIDO1 | |
| 1,2-Diisopentoxybenzene SCHEMBL2843498 | 0.90 | HTT (0.62) | HTTIDO1TDP1MCHR1TLR8 | |
| SCHEMBL21391871 | 0.87 | CYP1A2 (0.50) | CYP1A2CYP2C19CYP2C9HTTTDP1 | |
| 1-Isopentoxy-2-Ethoxybenzene SCHEMBL2844377 | 0.86 | L3MBTL1 (0.56) | CYP1A2CYP2C19HTTIDO1TDP1 | |
| 1,2-Dibutoxybenzene SCHEMBL1226749 | 0.85 | CYP1A2 (0.72) | CYP1A2CYP2C19CYP2C9TDP1MCHR1 | |
| 1,2-Dibutoxybenzene SCHEMBL29428927 | 0.85 | CYP1A2 (0.72) | CYP1A2CYP2C19CYP2C9TDP1MCHR1 | |
| SCHEMBL7931093 | 0.85 | CYP1A2 (0.56) | CYP1A2CYP2C19CYP2C9TDP1MCHR1 | |
| SCHEMBL19806810 | 0.84 | HTT (0.51) | CYP1A2CYP2C19CYP2C9HTTIDO1 | |
| 1,2-Dibutoxybenzene SCHEMBL6236324 | 0.83 | CYP1A2 (0.69) | CYP1A2CYP2C19CYP2C9TDP1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9497963-B2 | Methods and compositions for control of gypsy moth, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2016-11-22 | — | — | US | disclosed |
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | SIMON FRASER UNIVERSITY (CA) | 2013-02-21 | — | — | US | disclosed |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | SIMON FRASER UNIVERSITY (CA) | 2010-11-25 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045178-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTH, Lymantria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | CYP1A2 2344/4885CYP2C19 3989/4885CYP2C9 3051/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | CYP1A2 2220/4885CYP2C19 3786/4885CYP2C9 2754/4885 |
| US-20100297059-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, LYMANRIA DISPAR | L3MBTL3, L3MBTL4, L3MBTL1 | CYP1A2 2251/4885CYP2C19 3809/4885CYP2C9 2789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.