Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25600606 | 0.85 | — | — | |
| SCHEMBL25600603 | 0.85 | — | — | |
| SCHEMBL25600605 | 0.85 | — | — | |
| SCHEMBL9187883 | 0.81 | — | — | |
| SCHEMBL24838136 | 0.78 | — | — | |
| SCHEMBL25606058 | 0.78 | — | — | |
| SCHEMBL29172096 | 0.77 | ALDH1A1 (0.38) | OPRM1SPHK1FDPSTP53 | |
| SCHEMBL21925358 | 0.75 | TSHR (0.30) | — | |
| SCHEMBL598014 | 0.74 | TSHR (0.33) | OPRM1FDPS | |
| SCHEMBL18950020 | 0.73 | OPRM1 (0.44) | OPRM1SPHK1FDPSTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182698-A1 | TARGETING OF ENDOPLASMIC RETICULUM DYSFUNCTION AND PROTEIN FOLDING STRESS TO TREAT NEUROLOGICAL CONDITIONS | ALS THERAPY DEVELOPMENT INSTITUTE (US) | 2019-09-26 | — | — | WO | disclosed |