Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391990 | 0.80 | GAA (0.33) | — | |
| SCHEMBL21381436 | 0.78 | CTPS1 (0.42) | — | |
| SCHEMBL21392238 | 0.73 | ALDH1A1 (0.32) | CCNA2CDK2CCNA1 | |
| SCHEMBL21392067 | 0.70 | — | — | |
| SCHEMBL21381412 | 0.70 | CTSA (0.34) | CDK2 | |
| SCHEMBL21392000 | 0.68 | CTPS1 (0.43) | — | |
| SCHEMBL30415946 | 0.68 | CTPS1 (0.43) | — | |
| SCHEMBL21392086 | 0.62 | — | — | |
| SCHEMBL21392345 | 0.62 | CTPS1 (0.37) | — | |
| SCHEMBL21392156 | 0.60 | CTSA (0.34) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |