Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206208 | 1.00 | OPRM1 (0.46) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206217 | 0.97 | SIRT2 (0.47) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20206359 | 0.93 | SIRT2 (0.42) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206174 | 0.92 | OPRM1 (0.44) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20206243 | 0.92 | SIRT2 (0.41) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206350 | 0.92 | SIRT2 (0.41) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206182 | 0.91 | SIRT2 (0.44) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206203 | 0.91 | SIRT2 (0.42) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206178 | 0.89 | SIRT2 (0.40) | OPRM1OPRD1OPRK1SIRT2SIRT1 | |
| SCHEMBL20206247 | 0.89 | KEAP1 (0.41) | OPRM1OPRD1OPRK1SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183472-A1 | MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY | PALATIN TECHNOLOGIES, INC. (US) | 2019-09-26 | — | — | WO | disclosed |