SCHEMBL21392287

CCCC[C@H](NC(C)=O)C(=O)NC1CCC(=O)NCCC(C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)C(Cc2ccc(OC)cc2)NC(=O)CNC1=O

nearest known ligand 0.47

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	14/20	0.47

▸	FURIN	P09958	1/20	0.46

▸	SIRT2	Q8IXJ6	2/20	0.46

▸	SIRT1	Q96EB6	2/20	0.46

▸	SIRT3	Q9NTG7	2/20	0.46

▸	KEAP1	Q14145	1/20	0.45

▸	MC1R	Q01726	10/20	0.44

▸	MC3R	P41968	7/20	0.43

▸	MC5R	P33032	2/20	0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12092526	0.94	MC4R (0.48)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL21392454	0.93	MC4R (0.52)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL21392289	0.89	MC4R (0.45)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL12092650	0.87	MC4R (0.47)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL21392481	0.87	MC4R (0.47)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL12092579	0.87	MC4R (0.47)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL20362997	0.87	MC4R (0.47)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL12092735	0.87	MC4R (0.47)	MC4RFURINSIRT2SIRT1SIRT3
SCHEMBL20206361	0.86	MC4R (0.52)	MC4RFURINMC1RMC3RMC5R
SCHEMBL12092629	0.86	MC4R (0.52)	MC4RFURINMC1RMC3RMC5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2019183472-A1	MELANOCORTIN RECEPTOR-SPECIFIC PEPTIDE FORMULATIONS AND METHODS FOR GASTROINTESTINAL TRACT-SPECIFIC DELIVERY	PALATIN TECHNOLOGIES, INC. (US)	2019-09-26	—	—	WO	disclosed