Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003179 | 0.80 | PDE4A (0.46) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL19632376 | 0.80 | PDE4A (0.46) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL25457796 | 0.69 | CDK1 (0.36) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL10812168 | 0.66 | PDE4A (0.53) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL26925735 | 0.66 | CYP3A4 (0.66) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL30013079 | 0.65 | ADORA2A (0.46) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL25457076 | 0.64 | CDK1 (0.36) | ADORA2ACYP3A4CDK1MAPTTLR7 | |
| SCHEMBL30012191 | 0.63 | GRIN1 (0.35) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL9844553 | 0.63 | PDE4A (0.56) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| SCHEMBL1003427 | 0.63 | PARN (0.48) | CYP3A4BRD4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | VIRONGY, LLC | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292189-A1 | LIM KINASE INHIBITORS | LIMK1, LIMK2, LIMA1 | PDE4A 1477/4885ADORA2A 4797/4885PDE4B 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.