SCHEMBL21392513

SCHEMBL21392513

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(N(c4ccc5c(c4)C(c4ccccc4)(c4ccccc4)c4ccccc4-5)c4ccc5c(c4)oc4ccccc45)cc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.37
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
MAPT P10636 4/20 0.36
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
OPRK1 P41145 1/20 0.35
PTGER4 P35408 1/20 0.33
TTR P02766 1/20 0.32
PDK2 Q15119 2/20 0.32
ALOX5 P09917 1/20 0.32
MAOA P21397 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PGR P06401 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25124767 1.00 AHR (0.37) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL21392516 0.99 AHR (0.36) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL21141346 0.96 AHR (0.35) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL25145510 0.96 MEN1 (0.37) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL25145826 0.95 MEN1 (0.36) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL25145817 0.95 MEN1 (0.36) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL21559186 0.95 AHR (0.34) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL21037300 0.95 AHR (0.34) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL29774685 0.95 MEN1 (0.36) AHRMEN1KMT2AMAPTKDM4E
SCHEMBL24255765 0.94 AHR (0.33) AHRMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20230146354-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ORGANIC COMPOUND, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-05-11 US disclosed
US-20230146354-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ORGANIC COMPOUND, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-05-11 US disclosed
US-20230124044-A1 LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC APPLIANCE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2023-04-20 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 AHR 276/4885MEN1 1414/4885KMT2A 1198/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 AHR 276/4885MEN1 1414/4885KMT2A 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.