SCHEMBL21392546

SCHEMBL21392546

CCc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc4ccc5oc6ccccc6c5c4c3)c3ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
PSMD14 O00487 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MEN1 O00255 2/20 0.37
HPGD P15428 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
PDE10A Q9Y233 9/20 0.37
CYP1A2 P05177 1/20 0.37
RAB9A P51151 1/20 0.36
PTGER4 P35408 1/20 0.35
BMI1 P35226 1/20 0.34
MAPK1 P28482 3/20 0.33
HTT P42858 1/20 0.33
HKDC1 Q2TB90 1/20 0.33
DUSP3 P51452 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392576 0.94 PDE10A (0.39) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL21392592 0.92 PDE10A (0.41) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL21392433 0.91 PDE10A (0.38) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL26345601 0.91 PDE10A (0.40) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL21392533 0.89 POLB (0.41) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL21392547 0.89 MAPK1 (0.46) POLBL3MBTL1ALDH1A1SMN1; SMN2MEN1
SCHEMBL21392653 0.88 RECQL (0.41) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL17246878 0.87 PDE10A (0.39) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL26345621 0.87 MAPT (0.37) POLBL3MBTL1PSMD14RECQLALDH1A1
SCHEMBL17246909 0.87 PDE10A (0.38) POLBL3MBTL1PSMD14RECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-11877509-B2 Organic light-emitting element LG CHEM, LTD. 2024-01-16 US disclosed
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 POLB 2385/4885L3MBTL1 17/4885PSMD14 1482/4885
US-11877509-B2 Organic light-emitting element CRY1, CRY2, NR2E3 POLB 2385/4885L3MBTL1 17/4885PSMD14 1482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.