SCHEMBL21392662

SCHEMBL21392662

Cc1nc2ccccc2n1-c1ccc(-c2c3ccccc3c(-c3ccc(-c4ccncc4)cc3)c3ccc(-c4ccc5c(-c6ccc(-c7cccnc7)cc6)c6ccccc6c(-c6ccc(-n7c(C)nc8ccccc87)cc6)c5c4)cc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
G6PD P11413 1/20 0.42
MAPT P10636 8/20 0.42
ALOX12 P18054 1/20 0.42
AOC3 Q16853 1/20 0.40
PIK3CA P42336 2/20 0.40
MEN1 O00255 1/20 0.40
HSP90AA1 P07900 1/20 0.40
KMT2A Q03164 1/20 0.40
PIK3CD O00329 1/20 0.39
PIK3CB P42338 1/20 0.39
MTOR P42345 1/20 0.39
PIK3CG P48736 1/20 0.39
CYP11B2 P19099 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27000873 0.94 MAPT (0.42) MAPK1HTTG6PDMAPTALOX12
SCHEMBL21392517 0.92 MAPK1 (0.52) MAPK1HTTG6PDMAPTALOX12
SCHEMBL21392683 0.90 MAPK1 (0.49) MAPK1HTTMAPTPIK3CAMEN1
SCHEMBL26344511 0.90 MAPK1 (0.48) MAPK1HTTG6PDMAPTALOX12
SCHEMBL21392544 0.89 MAPT (0.44) G6PDMAPTAOC3PIK3CAMEN1
SCHEMBL26344381 0.87 MAPK1 (0.50) MAPK1HTTMAPTPIK3CAMEN1
SCHEMBL24674116 0.87 MAPK1 (0.58) MAPK1HTTMAPTPIK3CAMEN1
SCHEMBL21392593 0.87 MAPK1 (0.58) MAPK1HTTMAPTPIK3CAMEN1
SCHEMBL24674392 0.87 MAPK1 (0.58) MAPK1HTTMAPTPIK3CAMEN1
SCHEMBL10353294 0.87 MAPK1 (0.58) MAPK1HTTMAPTPIK3CAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296238-A1 Organic Light-emitting Element LG CHEM, LTD. (KR) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296238-A1 Organic Light-emitting Element CRY1, CRY2, NR2E3 MAPK1 4606/4885HTT 2428/4885G6PD 1438/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.