Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TET3 | O43151 | 3/20 | 0.50 |
| ▸ | FBXL19 | Q6PCT2 | 3/20 | 0.50 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.50 |
| ▸ | CXXC4 | Q9H2H0 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.50 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.47 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24490157 | 0.81 | CYP1A2 (0.45) | KMT2ANPC1RAB9ARYR2ESR1 | |
| SCHEMBL3893409 | 0.80 | ESR1 (0.75) | KMT2ANPC1RAB9AESR1ESR2 | |
| SCHEMBL22461208 | 0.80 | MEN1 (0.49) | KMT2ARYR2ESR1ESR2ABCB1 | |
| SCHEMBL10312979 | 0.79 | HRH3 (0.67) | KMT2ANPC1RAB9AACACBALOX5 | |
| SCHEMBL14781510 | 0.79 | ESR2 (0.67) | KMT2ANPC1RAB9AESR1ESR2 | |
| SCHEMBL22460958 | 0.79 | RYR2 (0.47) | KMT2ANPC1RAB9ARYR2ESR1 | |
| SCHEMBL30924689 | 0.79 | HRH3 (0.57) | NPC1RAB9APOLBHRH3BTK | |
| SCHEMBL27229575 | 0.79 | HRH3 (0.57) | NPC1RAB9APOLBHRH3BTK | |
| SCHEMBL24490162 | 0.79 | RYR2 (0.52) | KMT2ATET3FBXL19TET1KDM2B | |
| SCHEMBL25543001 | 0.79 | MAPT (0.51) | KMT2ANPC1RAB9ARYR2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2019183600-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | KMT2A 3168/4885TET3 4087/4885FBXL19 2571/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | KMT2A 3168/4885TET3 4087/4885FBXL19 2571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.