Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 5/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 3/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392995 | 0.86 | PNP (0.32) | ALDH1A1LMNAALBMAPK1PNP | |
| SCHEMBL21392993 | 0.83 | ADORA3 (0.42) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL30765431 | 0.77 | ADORA3 (0.44) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL22883526 | 0.76 | TYMP (0.47) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL28168146 | 0.76 | HPGD (0.41) | ALDH1A1LMNAPNPADORA3 | |
| SCHEMBL21859254 | 0.74 | TYMP (0.49) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL31160191 | 0.72 | TYMP (0.47) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL28168306 | 0.72 | PI4KA (0.43) | MAPK1ADORA3 | |
| SCHEMBL23487473 | 0.70 | TYMP (0.45) | ALDH1A1LMNAALBMAPK1ADORA3 | |
| SCHEMBL20548086 | 0.70 | TYMP (0.45) | ALDH1A1LMNAALBMAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242212-A2 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | Takeda Pharmaceutical Company Limited (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |