Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.38 |
| ▸ | TYMP | P19971 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765431 | 0.90 | ADORA3 (0.44) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL4374457 | 0.85 | ADORA3 (0.45) | ADORA3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL21392999 | 0.83 | ALDH1A1 (0.37) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL12878195 | 0.81 | ADORA2A (0.52) | ADORA3MAPK1MEN1KMT2A | |
| SCHEMBL12891153 | 0.81 | ADORA2A (0.52) | ADORA3MAPK1MEN1KMT2A | |
| SCHEMBL12878194 | 0.78 | SLC29A1 (0.39) | ADORA3LMNAMAPK1MEN1KMT2A | |
| SCHEMBL12891443 | 0.78 | SLC29A1 (0.39) | ADORA3LMNAMAPK1MEN1KMT2A | |
| SCHEMBL31421676 | 0.75 | ADORA3 (0.39) | ADORA3ALDH1A1LMNAALBMAPK1 | |
| SCHEMBL16258667 | 0.74 | ADORA3 (0.47) | ADORA3ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL116166 | 0.74 | ADORA3 (0.47) | ADORA3ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |