Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950632 | 0.98 | FFAR1 (0.30) | TDP1FFAR1CPT2 | |
| SCHEMBL21236727 | 0.92 | — | — | |
| SCHEMBL20123226 | 0.84 | EPHX1 (0.47) | EPHX1 | |
| SCHEMBL21393320 | 0.84 | EPHX1 (0.47) | EPHX1 | |
| SCHEMBL22791756 | 0.84 | KDM4E (0.32) | TDP1KDM4EMAPK1HIF1AEPHX1 | |
| SCHEMBL25720915 | 0.84 | EPHX1 (0.38) | TDP1KDM4EMAPK1HIF1AEPHX1 | |
| SCHEMBL27253956 | 0.82 | EPHX1 (0.43) | EPHX1 | |
| SCHEMBL19143353 | 0.81 | ADRA1A (0.36) | KDM4EMAPK1HIF1A | |
| SCHEMBL23175607 | 0.79 | MEN1 (0.32) | EPHX1 | |
| SCHEMBL18950854 | 0.79 | EPHX1 (0.39) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177466-A1 | DEGRADERS OF KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 (KEAP1) | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220177466-A1 | DEGRADERS OF KELCH-LIKE ECH-ASSOCIATED PROTEIN 1 (KEAP1) | KEAP1, NFE2L2, GSTK1 | TDP1 2171/4885FFAR1 3243/4885CPT2 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.