Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187436 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAGAAATM | |
| SCHEMBL26151369 | 0.71 | TDP1 (0.41) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL18171007 | 0.71 | KDM4E (0.43) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL22490108 | 0.68 | — | — | |
| SCHEMBL20203202 | 0.67 | MEN1 (0.37) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL27365834 | 0.66 | — | — | |
| SCHEMBL19616148 | 0.66 | AGXT (0.39) | KDM4EALDH1A1GLAGAA | |
| SCHEMBL22827595 | 0.64 | ALDH1A1 (0.37) | ALDH1A1GAA | |
| SCHEMBL12915143 | 0.64 | — | — | |
| SCHEMBL541849 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |