Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 3/20 | 0.32 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26155903 | 0.85 | TRPA1 (0.38) | JAK3POLBCYP2D6CYP1A2XDH | |
| SCHEMBL21393418 | 0.79 | SMN1; SMN2 (0.40) | POLBCYP2D6CYP1A2XDHALDH1A1 | |
| SCHEMBL21393365 | 0.79 | CYP3A4 (0.40) | POLBXDHALDH1A1 | |
| SCHEMBL26155899 | 0.76 | GDA (0.48) | JAK3POLBGDAALDH1A1 | |
| SCHEMBL21393574 | 0.75 | POLB (0.41) | POLBXDHGDAALDH1A1 | |
| SCHEMBL21393579 | 0.74 | LMNA (0.44) | POLB | |
| SCHEMBL26155912 | 0.71 | RECQL (0.46) | ALDH1A1 | |
| SCHEMBL21363641 | 0.67 | POLB (0.44) | POLBALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL21393345 | 0.67 | TRPA1 (0.39) | POLBXDHGDAALDH1A1 | |
| SCHEMBL21353905 | 0.66 | POLB (0.43) | JAK3POLBALDH1A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |