Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832461 | 0.72 | ALDH1A1 (0.34) | ALDH1A1LMNAPOLBNPSR1HTT | |
| SCHEMBL19964619 | 0.70 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL636356 | 0.69 | KMT2A (0.39) | ALDH1A1POLBNPSR1 | |
| SCHEMBL51396 | 0.68 | NPSR1 (0.57) | ALDH1A1LMNASMN1; SMN2NPSR1HTT | |
| SCHEMBL4977032 | 0.68 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL788049 | 0.68 | CA1 (0.37) | NPSR1 | |
| SCHEMBL12057417 | 0.67 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL21393711 | 0.67 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2POLBNPSR1 | |
| SCHEMBL4982115 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21393559 | 0.67 | ALDH1A1 (0.36) | ALDH1A1LMNASMN1; SMN2NPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | Phenex Discovery Verwaltungs-GmbH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | ALDH1A1 650/4885LMNA 4632/4885SMN1; SMN2 1421/4885 |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | ALDH1A1 650/4885LMNA 4632/4885SMN1; SMN2 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.